Comment on the webpage

[Admin]

Please leave your comment on the webpage here or any changes you want from your part.

[Herman]

At the bottom of my image on the techniques page put:

Re-printed with permission of NCBI.

Reference:
NCBI. Molecular Cell Biology. c2000 [Revised: 2008, March 14; cited 2008, March 22]. Available from: http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=mcb.figgrp.1437 .


By the way, every image should have some re-printed with permission of _____. underneath it (see page 40 in course manual).

[Herman]

Quiz Questions

1. Out of 100 Canadian women, how many will develop breast cancer in their lifetimes?
a) 1
b) 3
c) 5
d) 11

2. Males can get breast cancer: True or False?
a) True
b) False

3. What is the most common model used in GMO-based research?
a) Molluscs
b) Mice
c) Zebrafish
d) Fruitflies
e) Chimpanzees

4. HER2 and PTEN are what kinds of genes, respectively?
a) Both tumour-suppressors
b) Both oncogenes
c) Oncogene, Tumour-suppressor
d) Tumour-suppressor, Oncogene

5. Which one of the following is NOT an advantage of retrovirus vector use?
a) Specific integration into host genome
b) Specific targeting of dividing cells
c) Integrates into the genome, so all daughter cells contain viral DNA
d) Efficient delivery of genetic information.

6. The RNA interference mechanism can regulate expression at the level of:
a) DNA
b) Transcriptome
c) Proteome

Answers: DABCAB



See you guys in the meeting after lecture on Tuesday!

[asma.c]

For my image:
reprinted with the permission of : http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/T/TransgenicAnimals.html

[asma.c]

QUIZ QUESTION:

7. PTEN overexpression could potentially:
(a) induce tumour metastasis
(b) inhibit tumour metastasis
(c) suppress tumours
(d) Both (a) and (c)

8. Heterozygous germline mutations in PTEN are responsible for the Cowden disease, which results in:
(a) Mad Cow Disease
(b) High susceptibility to breast and thyroid carcinoma
(c) Brain abnormality
(d) Attraction to cattle farms

9. Genetic mouse-models most commonly used in Cancer research are:
(a) Knockout models
(b) Conditional models
(c) Transgenic models
(d) All of the above

10. Which of these continents boasts the highest incidence of breast cancer in women:
(a) Asia
(b) Africa
(c) North America
(d) Europe

Solutions: 7d, 8b, 9d, 10c